Article
Renin-angiotensin system gene polymorphisms: association with susceptibility to Henoch-Schonlein purpura and renal involvement.
Clinical rheumatology - 1 Nov 2006
Ozkaya Ozan, Söylemezoğlu Oğuz, Gönen Sevim, Misirlioğlu Müge, Tuncer Serdar, Kalman Süleyman, Buyan Necla, Hasanoğlu Enver
Abstract excerpt
The clinical course of Henoch-Schönlein Purpura (HSP) in children is variable, with some patients having a much more rapidly progressing course than others. We investigated whether polymorphisms of the renin-angiotensin system (RAS) genes are involved in HSP. Three RAS genotypes were examined in 114 children with HSP and in 164 healthy children: the angiotensin I converting enzyme (ACE) insertion/deletion...
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