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Article

Correlation of MIC with Outcome for <i>Candida</i> Species Tested against Voriconazole: Analysis and Proposal for Interpretive Breakpoints

1 Mar 2006

Abstract excerpt

Developing interpretive breakpoints for any given organism-drug combination requires integration of the MIC distribution, pharmacokinetic and pharmacodynamic parameters, and the relationship between the in vitro activity and outcome from both in vivo and clinical studies. Using data generated by standardized broth microdilution and disk diffusion test methods, the Antifungal Susceptibility Subcommittee of the...

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PMID: 16517860
DOI: 10.1128/jcm.44.3.819-826.2006

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