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Article

Definitive Evidence for the Nonmitochondrial Production of Superoxide Anion by Human Spermatozoa

28 Feb 2006

Abstract excerpt

CONTEXT: Oxidative stress in the male germ line has been associated with poor fertility, impaired embryonic development, miscarriage, and childhood disease. Such stress is known to be associated with the peroxidation of unsaturated fatty acids in the sperm plasma membrane and oxidative DNA damage to both the nuclear and mitochondrial genomes. However, the source of the free radicals responsible for such damage is...

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Identifiers

PMID: 16507629
DOI: 10.1210/jc.2005-2711

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