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Article

Significance of Mitochondrial Reactive Oxygen Species in the Generation of Oxidative Stress in Spermatozoa

21 May 2008

Abstract excerpt

CONTEXT: Male infertility has been linked with the excessive generation of reactive oxygen species (ROS) by defective spermatozoa. However, the subcellular origins of this activity are unclear. OBJECTIVE: The objective of this study was to determine the importance of sperm mitochondria in creating the oxidative stress associated with defective sperm function. METHOD: Intracellular measurement of mitochondrial ROS...

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Identifiers

PMID: 18492763
DOI: 10.1210/jc.2007-2616

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