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Article

A deficiency in the region homologous to human 17q21.33-q23.2 causes heart defects in mice.

Genetics - 1 May 2006

Yu Y Eugene, Morishima Masae, Pao Annie, Wang Ding-Yan, Wen Xiao-Yan, Baldini Antonio, Bradley Allan

Abstract excerpt

Several constitutional chromosomal rearrangements occur on human chromosome 17. Patients who carry constitutional deletions of 17q21.3-q24 exhibit distinct phenotypic features. Within the deletion interval, there is a genomic segment that is bounded by the myeloperoxidase and homeobox B1 genes. This genomic segment is syntenically conserved on mouse chromosome 11 and is bounded by the mouse homologs of the same...

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Identifiers

PMID: 16489219
DOI: 10.1534/genetics.105.054833
PMCID: PMC1461454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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