Immunohistochemical evaluation of conjunctival fibrillin-1 in Marfan syndrome.

doi:10.1001/archopht.124.2.205

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Article

Immunohistochemical evaluation of conjunctival fibrillin-1 in Marfan syndrome.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Feb 2006

Ganesh Anuradha, Smith Charles, Chan Wilson, Unger Sheila, Quercia Nada, Godfrey Maurice, Kraft Stephen, Buncic Raymond, Levin Alex

Abstract excerpt

OBJECTIVE: To evaluate status of conjunctival fibrillin-1 in patients with Marfan syndrome with ectopia lentis. METHODS: Frozen sections of conjunctiva from 6 patients with Marfan syndrome with ectopia lentis and from 15 age-matched control subjects were stained with mouse antihuman fibrillin-1 antibody, using an avidin biotin immunoperoxidase technique. The fibrillin-1 staining characteristics of conjunctiva...

Topics

Adolescent
Adult
Biopsy
Conjunctiva
Ectopia Lentis
Extracellular Matrix Proteins
Eye Proteins
Fibrillin-1
Fibrillins
Humans
Immunoenzyme Techniques
Marfan Syndrome
Microfilament Proteins
Mutation

Source

Open in PubMed

Identifiers

PMID: 16476890
DOI: 10.1001/archopht.124.2.205

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