Article
Phenotypic alterations and survival of monocytes following infection by human herpesvirus-6.
Archives of virology - 1 Aug 2006
Janelle M-E, Flamand L
Abstract excerpt
Freshly isolated monocytes rapidly undergo physiological changes in vitro, resulting in programmed cell death (apoptosis). Activation of monocytes, which promotes differentiation into macrophages, is known to inhibit apoptotic processes. In the present study, we report that human herpesvirus-6 (HHV-6) prevents monocytes from undergoing spontaneous apoptosis during the first 72 hours of culture. Furthermore,...
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