Article
Apolipoprotein E, angiotensin-converting enzyme and kallikrein gene polymorphisms and the risk of Alzheimer's disease and vascular dementia.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Oct 2006
Wang H K, Fung H C, Hsu W C, Wu Y R, Lin J C, Ro L S, Chang K H, Hwu F J, Hsu Y, Huang S Y, Lee-Chen G J, Chen C M
Abstract excerpt
Lipoproteins and vascular factors may play roles in the development of Alzheimer's disease (AD) and/or vascular dementia (VaD). In this study, odd ratios (ORs) and 95% confidence intervals (CIs) for apolipoprotein E (APOE), angiotensin-converting enzyme (ACE), and kallikrein (KLK1) polymorphisms were computed to test their association with the disease by a case-control study. The risk of AD was significantly...
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