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Article

Domains of Importin-alpha2 required for ring canal assembly during Drosophila oogenesis.

Journal of structural biology - 1 Apr 2006

Gorjánácz Mátyás, Török István, Pomozi István, Garab Gyozo, Szlanka Tamás, Kiss István, Mechler Bernard M

Abstract excerpt

Null-mutation in Drosophila importin-alpha2, such as the deficiency imp-alpha2(D14), causes recessive female sterility with the formation of dumpless eggs. In imp-alpha2(D14) the transfer of nurse cell components to the oocyte is interrupted and the Kelch protein, an oligomeric ring canal actin organizer, is normally produced but fails to associate with the ring canals resulting in their occlusion. To define...

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PMID: 16458020
DOI: 10.1016/j.jsb.2005.12.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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