Article
Serologic and genetic markers of celiac disease: a sequential study in the screening of first degree relatives.
Journal of pediatric gastroenterology and nutrition - 1 Feb 2006
Bonamico Margherita, Ferri Mirella, Mariani Paolo, Nenna Raffaella, Thanasi Enina, Luparia Rita P L, Picarelli Antonio, Magliocca Fabio M, Mora Barbara, Bardella Maria Teresa, Verrienti Antonella, Fiore Benedetta, Uccini Stefania, Megiorni Francesca, Mazzilli Maria Cristina, Tiberti Claudio
Abstract excerpt
OBJECTIVES: The prevalence of celiac disease (CD) among the relatives and the complications of an undiagnosed CD prompted us to identify a useful disease screening strategy. METHODS: We studied 441 first degree relatives of 208 CD patients by immunoglobulin (Ig)A antiendomysium antibodies (EMA) and radioimmunoprecipitation assay (RIA) IgA antitransglutaminase autoantibodies (TGAA). Of these, 364 were typed for...
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