Article
Linkage disequilibrium across two different single-nucleotide polymorphism genome scans.
BMC genetics - 30 Dec 2005
Peralta Juan Manuel, Dyer Thomas D, Warren Diane M, Blangero John, Almasy Laura
Abstract excerpt
Linkage disequilibrium (LD) content was calculated for the Genetic Analysis Workshop 14 Affymetrix and Illumina single-nucleotide polymorphism (SNP) genome scans of the Collaborative Study on the Genetics of Alcoholism samples. Pair-wise LD was measured as both D' and r2 on 505 pedigree founder individuals. The r2 estimates were then used to correct the multipoint identity by descent matrix (MIBD) calculation to...
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