Article
Surrogate phenotype definition for alcohol use disorders: a genome-wide search for linkage and association.
BMC genetics - 30 Dec 2005
Rosenberger Albert, Janicke Nico, Köhler Karola, Korb Katrin, Kulle Bettina, Bickeböller Heike
Abstract excerpt
For the identification of susceptibility loci in complex diseases the choice of the target phenotype is very important. We compared results of genome-wide searches for linkage or for association related to three phenotypes for alcohol use disorder. These are a behavioral score BQ, based on a 12-i...
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