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Article

Thyroid Hormone Resistance in children.

Pediatric endocrinology reviews : PER - 1 Dec 2003

Ercan Oya

Abstract excerpt

Thyroid Hormone Resistance (RTH) is characterized by the diminished response of thyroid hormone-responsive tissues in varying degrees in association with elevated serum levels of total and free T4 and T3 and inappropriately normal or elevated TSH levels. In almost all cases it is due to different mutations in only one allele of the thyroid hormone receptor beta gene which blocks the action of normal allele thus...

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PMID: 16444158

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