Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell cycle regulators and apoptosis-associated proteins in relation to proliferative activity and degree of apoptosis in HNPCC versus sporadic endometrial carcinoma.

Histopathology - 1 Feb 2006

Rijcken F, van der Zee A, van der Sluis T, Boersma-van Ek W, Kleibeuker J, Hollema H

Abstract excerpt

AIMS: Mismatch repair gene malfunction occurs early in the carcinogenesis of hereditary non-polyposis colorectal cancers (HNPCCs), leading to an accelerated accumulation of mutations and possibly to change in expression of cell cycle proteins. There is strong evidence that tumorigenesis in HNPCCs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Adenocarcinoma, Clear Cell
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to bcl-2-Associated X Protein

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to Cyclin B

Share to Cyclin B1

Share to Endometrial Neoplasms

Source

Identifiers

PMID: 16430474
DOI: 10.1111/j.1365-2559.2005.02324.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16430474-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell cycle regulators and apoptosis-associated proteins in relation to proliferative activity and degree of apoptosis in HNPCC versus sporadic endometrial carcinoma.PMID 16430474Read ↗

Pathologic features of endometrial carcinoma associated with HNPCC: a comparison with sporadic endometrial carcinoma.Semantic proximity Read ↗

Cell Proliferation and Apoptosis in BRCA-Associated Hereditary Ovarian CancerSemantic proximity Read ↗

Expression of differentiation and proliferation related proteins in epithelium of prophylactically removed ovaries from women with a hereditary female adnexal cancer predisposition.Semantic proximity Read ↗

Survival of hereditary non-polyposis colorectal cancer patients compared with sporadic colorectal cancer patientsSemantic proximity Read ↗

Molecular analysis in endometrial cancer.Semantic proximity Read ↗

Relationship between PTEN, DNA mismatch repair, and tumor histotype in endometrial carcinoma: retained positive expression of PTEN preferentially identifies sporadic non-endometrioid carcinomasSemantic proximity Read ↗

Hereditary and somatic DNA mismatch repair gene mutations in sporadic endometrial carcinomaSemantic proximity Read ↗

Apoptotic and growth regulatory genes as mutational targets in mismatch repair deficient endometrioid adenocarcinomas of young patients.Semantic proximity Read ↗

Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma.Semantic proximity Read ↗

Loss of p21WAF1/Cip1 protein expression accompanies progression of sporadic colorectal neoplasms but not hereditary nonpolyposis colorectal cancers.Semantic proximity Read ↗

KRAS, p53 and BRAF gene mutations and aneuploidy in sporadic colorectal cancer progression.Semantic proximity Read ↗

Survival of patients with ovarian cancer due to a mismatch repair defect.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.