Article
Temporal changes in streptococcal M protein types and the near-disappearance of acute rheumatic fever in the United States.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Feb 2006
Shulman Stanford T, Stollerman Gene, Beall Bernard, Dale James B, Tanz Robert R
Abstract excerpt
BACKGROUND: The explanation for the very substantial decrease in the incidence of acute rheumatic fever in the United States, particularly over the past 50 years, is unclear. It has been proposed that certain M types of group A streptococci (GAS) include strains that are particularly rheumatogenic and that others are nonrheumatogenic. METHODS: We compared the M type distribution of GAS recovered from children...
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