Article
Metabolic regulation of type III secretion gene expression in Pseudomonas aeruginosa.
Molecular microbiology - 1 Feb 2006
Rietsch Arne, Mekalanos John J
Abstract excerpt
Type III secretion-mediated cytotoxicity is one of the key virulence mechanisms of the opportunistic pathogen Pseudomonas aeruginosa. Prior data from several laboratories have established that metabolism is a key factor in the regulation of type III secretion gene expression in P. aeruginosa. Here we use a fluorescence-activated cell sorter (FACS)-based approach to investigate expression of type III secretion...
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