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Article

The mouse forkhead gene Foxc1 is required for primordial germ cell migration and antral follicle development.

Developmental biology - 15 Feb 2006

Mattiske Deidre, Kume Tsutomu, Hogan Brigid L M

Abstract excerpt

Foxc1 encodes a forkhead/winged helix transcription factor expressed in many embryonic tissues. Previous studies have investigated defects in the urogenital system of Foxc1 null mutants, but the mechanisms underlying the abnormal development of the gonad have not been explored. From earliest stages, the mutant ovaries are smaller than normal, with fewer germ cells and disorganized somatic issue. No bursa membrane...

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Identifiers

PMID: 16412416
DOI: 10.1016/j.ydbio.2005.12.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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