Article
Genetic and environmental influences on objective intermediate asthma phenotypes in Dutch twins.
The European respiratory journal - 1 Aug 2010
Wu T, Boezen H M, Postma D S, Los H, Postmus P E, Snieder H, Boomsma D I
Abstract excerpt
It is unclear to what extent the same set of environmental or genetic factors regulate objective intermediate asthma phenotypes. We examined heritabilities of these phenotypes and estimated their environmental and genetic overlap. We studied baseline lung function (forced expiratory volume in 1 s (FEV(1)), forced vital capacity (FVC) and FEV(1)/FVC), bronchial hyperresponsiveness, number of positive skin prick...
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