Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Serum Opacity Factor, a Streptococcal Virulence Factor That Binds to Apolipoproteins A-I and A-II and Disrupts High Density Lipoprotein Structure

4 Jan 2006

Abstract excerpt

Serum opacity factor (SOF) is a virulence determinant of group A streptococci that opacifies mammalian sera. We analyzed the specificity and mechanism of the opacity reaction using a recombinant form of the amino-terminal opacification domain of SOF, rSOF. Our data indicate that rSOF is neither a protease nor a lipase, but rather it is the binding of rSOF to high density lipoprotein (HDL) that triggers the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammasome and immune disorders
Share to Neonatal and Maternal Infections
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16407233
DOI: 10.1074/jbc.m512538200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Serum Opacity Factor, a Streptococcal Virulence Factor That Binds to Apolipoproteins A-I and A-II and Disrupts High Density Lipoprotein StructurePMID 16407233Read ↗

The Structure and Function of Serum Opacity Factor: A Unique Streptococcal Virulence Determinant That Targets High-Density LipoproteinsSemantic proximity Read ↗

Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence.Semantic proximity Read ↗

Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete.Semantic proximity Read ↗

Identification of a Novel Virulence Determinant with Serum Opacification Activity in<i>Streptococcus suis</i>Semantic proximity Read ↗

Molecular Genetic Analysis of a Group A Streptococcus Operon Encoding Serum Opacity Factor and a Novel Fibronectin-Binding Protein, SfbXSemantic proximity Read ↗

Serratamolide is a hemolytic factor produced by Serratia marcescens.Semantic proximity Read ↗

Apolipoprotein A-I exerts bactericidal activity against Yersinia enterocolitica serotype O:3.Semantic proximity Read ↗

Crystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat.Semantic proximity Read ↗

Is streptolysin S of group A streptococci a virulence factor?Semantic proximity Read ↗

Human Complement Factor H Binds to Outer Membrane Protein Rck of SalmonellaSemantic proximity Read ↗

Variation of the serum opacity factor locus (sof) of Streptococcus pyogenes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.