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Article

Retrotransposon insertion in SILV is responsible for merle patterning of the domestic dog.

Proceedings of the National Academy of Sciences of the United States of America - 31 Jan 2006

Clark Leigh Anne, Wahl Jacquelyn M, Rees Christine A, Murphy Keith E

Abstract excerpt

Merle is a pattern of coloring observed in the coat of the domestic dog and is characterized by patches of diluted pigment. This trait is inherited in an autosomal, incompletely dominant fashion. Dogs heterozygous or homozygous for the merle locus exhibit a wide range of auditory and ophthalmologic abnormalities, which are similar to those observed for the human auditory-pigmentation disorder Waardenburg...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16407134
DOI: 10.1073/pnas.0506940103
PMCID: PMC1360527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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