Article
Low variability of the POLG (CAG)n repeat in north Eurasian populations.
Human biology - 1 Jun 2005
Malyarchuk Boris A, Papuga Marta, Grzybowski Tomasz, Rogozin Igor B, Wozniak Marcin, Derenko Miroslava V, Rychkov Serge Yu, Czarny Jakub, Zakharov Ilia A, Miścicka-Sliwka Danuta
Abstract excerpt
We investigated the frequency of different repeat-length alleles of the trinucleotide CAG microsatellite repeat in the coding sequence of the nuclear gene for the catalytic subunit of mitochondrial DNA polymerase gamma (POLG) in 12 ethnic groups from northern Eurasia. The population sample consisted of 1,330 individuals from 3 large geographic areas: Europe, Southwest Asia, and Siberia/East Asia. We found that...
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