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Article

Genomic signature induced by pregnancy in the human breast

1 Feb 2006

Abstract excerpt

We have postulated that the lifetime protective effect of an early pregnancy against breast cancer is due to the complete differentiation of the mammary gland characterized by a specific genomic signature imprinted by the physiological process of pregnancy. For demonstrating this hypothesis we compared the genomic profile of the epithelium and the stroma of normal breast tissues from reduction mammoplasties...

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Identifiers

PMID: 16391795
DOI: 10.3892/ijo.28.2.399

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