Replication and Long-Term Persistence of Bovine and Human Strains of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> within <i>Acanthamoeba polyphaga</i>

Abstract excerpt

Free-living protists are ubiquitous in the environment and form a potential reservoir for the persistence of animal and human pathogens. Mycobacterium avium subsp. paratuberculosis is the cause of Johne's disease, a systemic infection accompanied by chronic inflammation of the intestine that affects many animals, including primates. Most humans with Crohn's disease are infected with this chronic enteric pathogen....

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