Article
Phenotypic diversity of the lung vasculature in experimental models of metastases.
Chest - 1 Dec 2005
Oh Yun, Mohiuddin Imran, Sun Yan, Putnam Joseph B, Hong Waun Ki, Arap Wadih, Pasqualini Renata
Abstract excerpt
In vivo phage display is a screening method in which peptides homing to specific vascular beds are selected after IV administration of a random peptide library. This strategy has revealed a vascular address system that allows tissue-specific targeting of normal blood vessels and angiogenesis-related targeting of tumor blood vessels by selected peptides. Many vascular receptors or "addresses" targeted by homing...
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