Steps toward mapping the human vasculature by phage display.

doi:10.1038/nm0202-121

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Article

Steps toward mapping the human vasculature by phage display.

Nature medicine - 1 Feb 2002

Arap Wadih, Kolonin Mikhail G, Trepel Martin, Lahdenranta Johanna, Cardó-Vila Marina, Giordano Ricardo J, Mintz Paul J, Ardelt Peter U, Yao Virginia J, Vidal Claudia I, Chen Limor, Flamm Anne, Valtanen Heli, Weavind Lisa M, Hicks Marshall E, Pollock Raphael E, Botz Gregory H, Bucana Corazon D, Koivunen Erkki, Cahill Dolores, Troncoso Patricia, Baggerly Keith A, Pentz Rebecca D, Do Kim-Anh, Logothetis Christopher J, Pasqualini Renata

Abstract excerpt

The molecular diversity of receptors in human blood vessels remains largely unexplored. We developed a selection method in which peptides that home to specific vascular beds are identified after administration of a peptide library. Here we report the first in vivo screening of a peptide library in a patient. We surveyed 47,160 motifs that localized to different organs. This large-scale screening indicates that...

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PMID: 11821895
DOI: 10.1038/nm0202-121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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