Article
A sigma28-regulated nonflagella gene contributes to virulence of Campylobacter jejuni 81-176.
Infection and immunity - 1 Jan 2006
Goon Scarlett, Ewing Cheryl P, Lorenzo Maria, Pattarini Dawn, Majam Gary, Guerry Patricia
Abstract excerpt
A Campylobacter jejuni 81-176 mutant in Cj0977 was fully motile but reduced >3 logs compared to the parent in invasion of intestinal epithelial cells in vitro. The mutant was also attenuated in a ferret diarrheal disease model. Expression of Cj0977 protein was dependent on a minimal flagella structure.
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