Article
A receptor-binding protein of Campylobacter jejuni bacteriophage NCTC 12673 recognizes flagellin glycosylated with acetamidino-modified pseudaminic acid.
Molecular microbiology - 1 Jan 2015
Javed Muhammad Afzal, van Alphen Lieke B, Sacher Jessica, Ding Wen, Kelly John, Nargang Cheryl, Smith David F, Cummings Richard D, Szymanski Christine M
Abstract excerpt
Bacteriophage receptor-binding proteins (RBPs) confer host specificity. We previously identified a putative RBP (Gp047) from the campylobacter lytic phage NCTC 12673 and demonstrated that Gp047 has a broader host range than its parent phage. While NCTC 12673 recognizes the capsular polysaccharide (CPS) of a limited number of Campylobacter jejuni isolates, Gp047 binds to a majority of C. jejuni and related...
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