Article
The lpf gene cluster for long polar fimbriae is not involved in adherence of enteropathogenic Escherichia coli or virulence of Citrobacter rodentium.
Infection and immunity - 1 Jan 2006
Tatsuno Ichiro, Mundy Rosanna, Frankel Gad, Chong Yuwen, Phillips Alan D, Torres Alfredo G, Kaper James B
Abstract excerpt
Using the enteropathogenic Escherichia coli (EPEC) genome sequence, we found that EPEC E2348/69 has an lpfABCDE gene cluster homologous (about 60% identical at the protein level) to the Salmonella long polar fimbria (LPF) operon. To determine whether this operon is essential for adherence, the lpfABCD(E2)(3) genes were deleted from EPEC strain E2348/69 by allelic exchange. Analysis of the resulting...
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