Article
Relationship of p22phox C242T polymorphism with nephropathy in type 2 diabetic patients.
Journal of nephrology - 1 Jan 2000
Santos Kátia G, Canani Luís H, Gross Jorge L, Tschiedel Balduíno, Souto Kátia E, Roisenberg Israel
Abstract excerpt
BACKGROUND: In this case-control study, we investigated the possible involvement of the p22phox C242T polymorphism in the development and progression of diabetic nephropathy (DN) in 535 Caucasian Brazilians with type 2 diabetes. We also evaluated the effects of the interaction of the C242T polymorphism with smoking and hypercholesterolemia on the susceptibility to nephropathy. METHODS: Genotype analysis was...
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