Article
Genetic variation in the sodium-dependent vitamin C transporters, SLC23A1, and SLC23A2 and risk for preterm delivery.
American journal of epidemiology - 1 Feb 2006
Erichsen Hans Christian, Engel Stephanie A Mulherin, Eck Peter K, Welch Robert, Yeager Meredith, Levine Mark, Siega-Riz Anna Maria, Olshan Andrew F, Chanock Stephen J
Abstract excerpt
Vitamin C has been the focus of epidemiologic investigation in preterm delivery (<37 weeks' gestation), which is a leading cause of neonatal mortality and birth-related morbidity. There are two sodium-dependent membrane transporters encoded by SLC23A1 and SLC23A2, which have key roles in human vitamin C metabolism and which control dietary uptake, reabsorption, and tissue distribution of vitamin C. Using maternal...
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