Article
Diversity of long-chain toxins in Tityus zulianus and Tityus discrepans venoms (Scorpiones, Buthidae): molecular, immunological, and mass spectral analyses.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Jan 2000
Borges Adolfo, García Carmen C, Lugo Elizabeth, Alfonzo Marcelo J, Jowers Michael J, Op den Camp Huub J M
Abstract excerpt
In Venezuela, stings by Tityus zulianus scorpions produce cardiorespiratory arrest, whereas envenoming by Tityus discrepans involves gastrointestinal/pancreatic complications, suggesting structural and/or functional differences. We sought to compare their toxin repertoires through immunological, molecular, and mass spectral analyses. First, in vivo tests showed that neutralization of T. zulianus venom toxicity by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.