Origin and diversification of minisatellites derived from human Alu sequences.

doi:10.1016/j.gene.2005.09.029

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Article

Origin and diversification of minisatellites derived from human Alu sequences.

Gene - 3 Jan 2006

Jurka Jerzy, Gentles Andrew J

Abstract excerpt

We analyze minisatellites derived from Alu fragments corresponding approximately to the first 44 bases of human Alu consensus sequences from different subfamilies. The origin of Alu-derived minisatellites appears to have been mediated by short flanking repeats, as first proposed by Haber and Louis [Haber, J.E., Louis, E.J., 1998. Minisatellite origins in yeast and humans. Genomics 48, 132-135.]. We also present...

Topics

Alu Elements
Amino Acid Sequence
Base Sequence
Chromosomes, Human, Pair 20
Chromosomes, Human, Pair 22
Consensus Sequence
Evolution, Molecular
Gene Conversion
Genetic Variation
Genome, Human
Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Minisatellite Repeats

Molecular Sequence Data

Mutagenesis, Insertional

Sequence Deletion

Sequence Homology, Amino Acid

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 16343813
DOI: 10.1016/j.gene.2005.09.029

Provenance

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