Article
A new alpha chain variant, Hb Turriff [alpha 99(G6)Lys----Glu]: the interference of abnormal hemoglobins in Hb A1c determination.
Hemoglobin - 1 Jan 1992
Langdown J V, Davidson R J, Williamson D
Abstract excerpt
Hb Turriff is a new hemoglobin variant which we have identified in a diabetic individual. During the determination of Hb A1c by high performance liquid chromatography, an inappropriately elevated result was found to be due to the abnormal hemoglobin chromatographing with the Hb A1c fraction. This...
Topics
- Adult
- Amino Acid Sequence
- Chromatography, High Pressure Liquid
- Diabetes Mellitus
- Female
- Globins
- Glycated Hemoglobin
- Hemoglobins, Abnormal
- Humans
- Molecular Sequence Data
- Mutation
