Article
Interaction between the X chromosome and an autosome regulates size sexual dimorphism in Portuguese Water Dogs.
Genome research - 1 Dec 2005
Chase Kevin, Carrier David R, Adler Frederick R, Ostrander Elaine A, Lark Karl G
Abstract excerpt
Size sexual dimorphism occurs in almost all mammals. In Portuguese Water Dogs, much of the difference in skeletal size between females and males is due to the interaction between a Quantitative Trait Locus (QTL) on the X-chromosome and a QTL linked to Insulin-like Growth Factor 1 (IGF-1) on the CFA 15 autosome. In females, the haplotype of CFA 15 resulting in small size is dominant. In males, the haplotype for...
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