Article
Expression of interleukin-8 receptors (CXCR1 and CXCR2) in premenopausal women with recurrent urinary tract infections.
Clinical and diagnostic laboratory immunology - 1 Dec 2005
Smithson Alex, Sarrias Maria Rosa, Barcelo Juanjo, Suarez Belen, Horcajada Juan Pablo, Soto Sara Maria, Soriano Alex, Vila Jordi, Martinez Jose Antonio, Vives Jordi, Mensa Jose, Lozano Francisco
Abstract excerpt
The migration of neutrophils through infected tissues is mediated by the CXC chemokines and its receptors (CXCR1 and CXCR2). It has been proposed that a CXCR1 deficiency could confer susceptibility to acute pyelonephritis in children. The objective of the study is to assess the surface expression of CXCR1 and CXCR2 and the existence of polymorphisms in the CXCR1 gene in premenopausal women with recurrent urinary...
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