Article
Expression of FGF23 is correlated with serum phosphate level in isolated fibrous dysplasia.
Life sciences - 11 Apr 2006
Kobayashi Keisuke, Imanishi Yasuo, Koshiyama Hiroyuki, Miyauchi Akimitsu, Wakasa Kenichi, Kawata Takehisa, Goto Hitoshi, Ohashi Hirotsugu, Koyano Hajime M, Mochizuki Ryuichi, Miki Takami, Inaba Masaaki, Nishizawa Yoshiki
Abstract excerpt
Fibrous dysplasia (FD) patients sometimes suffer from concomitant hypophosphatemic rickets/osteomalacia, resulting from renal phosphate wasting. It was recently reported that FD tissue in the patients with McCune-Albright syndrome (MAS) expressed fibroblast growth factor-23 (FGF-23), which is now known to be as a pathogenic phosphaturic factor in patients with oncogenic osteomalacia and X-linked hypophosphatemic...
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