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Article

Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli.

The American journal of clinical nutrition - 1 Dec 2005

Gasper Amy V, Al-Janobi Ahmed, Smith Julie A, Bacon James R, Fortun Paul, Atherton Clare, Taylor Moira A, Hawkey Christopher J, Barrett David A, Mithen Richard F

Abstract excerpt

BACKGROUND: Broccoli consumption is associated with a reduction in the risk of cancer, particularly in persons with a functional glutathione S-transferase M1 allele, as opposed rotrose whose GSTM1 gene has been deleted. Sulforaphane, the major isothiocyanate derived from 4-methylsulfinylbutyl glucosinolate, is thought to be the main agent conferring protection. OBJECTIVE: We compared sulforaphane metabolism in...

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Source

Identifiers

PMID: 16332662
DOI: 10.1093/ajcn/82.6.1283

Genes

GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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