Article
Multiple gastric stromal tumors in a child without syndromic association lacks common KIT or PDGFRalpha mutations.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society - 1 Jan 2000
O'Sullivan Maureen J, McCabe Amanda, Gillett Peter, Penman Iain D, MacKinlay Gordon A, Pritchard Jon
Abstract excerpt
A diagnosis of multiple gastric stromal tumors that were nonmetastatic at presentation was made in an 11-year-old girl who presented with hematemesis. Gastrointestinal stromal tumor (GIST) is a rare diagnosis in childhood and reported multiple lesions are generally seen in the context of familial disease, occasionally with syndromic associations. Although there are no reports of genetic mutation in cases of...
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