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Article

Peripheral nerve and skeletal muscle involvement in CADASIL.

Acta neuropathologica - 1 Dec 2005

Schröder J M, Züchner S, Dichgans M, Nagy Z, Molnar M J

Abstract excerpt

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is characterized by degeneration of vascular smooth muscle cells (VSMC) of nearly all tissues studied so far. The clinical phenotype of CADASIL shows great variability. The disease is caused by mutations of the Notch3 gene encoding the transmembrane receptor Notch3, which is expressed predominantly in VSMC. In...

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Source

Identifiers

PMID: 16328531
DOI: 10.1007/s00401-005-1082-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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