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Article

The role of vesicular transport in ABCA1-dependent lipid efflux and its connection with NPC pathways.

Journal of molecular medicine (Berlin, Germany) - 1 Apr 2006

Boadu Emmanuel, Francis Gordon A

Abstract excerpt

The membrane transporter ATP-binding cassette transporter A1 (ABCA1) has been shown to be the rate-limiting step in the initial formation of plasma high-density lipoprotein (HDL) particles. The mechanisms of action of ABCA1, including its role in the vesicular transport of lipids to the cell surface for the lipidation of HDL apolipoproteins, are not fully understood. Niemann-Pick type C (NPC) disease is most...

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Share to ATP Binding Cassette Transporter 1
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16328207
DOI: 10.1007/s00109-005-0001-9

Genes

ABCA1
NPC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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