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Article

Identification of an Na <sub>v</sub> 1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures

2 Dec 2005

Abstract excerpt

Febrile seizures (FS) affect 5-12% of infants and children up to 6 years of age. There is now epidemiological evidence that FS are associated with subsequent afebrile and unprovoked seizures in approximately 7% of patients, which is 10 times more than in the general population. Extensive genetic studies have demonstrated that various loci are responsible for familial FS, and the FEB3 autosomal-dominant locus has...

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PMID: 16326807
DOI: 10.1073/pnas.0506818102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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