Bioprocess Engineering Issues That Would Be Faced in Producing a DNA Vaccine at up to 100 m³ Fermentation Scale for an Influenza Pandemic

Abstract excerpt

The risk of a pandemic with a virulent form of influenza is acknowledged by the World Health Organization (WHO) and other agencies. Current vaccine production facilities would be unable to meet the global requirement for vaccine. As a possible supplement a DNA vaccine may be appropriate, and bioprocess engineering factors bearing on the use of existing biopharmaceutical and antibiotics plants to produce it are...

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