Article
Coeliac disease: a diverse clinical syndrome caused by intolerance of wheat, barley and rye.
The Proceedings of the Nutrition Society - 1 Nov 2005
McGough Norma, Cummings John H
Abstract excerpt
Coeliac disease is a lifelong intolerance to the gluten found in wheat, barley and rye, and some patients are also sensitive to oats. The disease is genetically determined, with 10% of the first-degree relatives affected and 75% of monozygotic twins being concordant. Of the patients with coeliac disease 95% are human leucocyte antigen (HLA)-DQ2 or HLA-DQ8 positive. Characteristically, the jejunal mucosa becomes...
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