A fibrin matrix modulates the proliferation, hormone secretion and morphologic differentiation of cultured human placental trophoblast.

doi:10.1016/0143-4004(92)90031-n

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Article

A fibrin matrix modulates the proliferation, hormone secretion and morphologic differentiation of cultured human placental trophoblast.

Placenta - 1 Jan 2000

Farmer D R, Nelson D M

Abstract excerpt

Term placental trophoblast epithelialize fibrin deposits attached to villi in vitro and trophoblast cultured on a fibrin matrix form an epithelial bilayer typical of the trophoblast layer on term villi. We compared the morphology of cells grown on fibrin with cells grown on substrates of type IV...

Topics

Cell Differentiation
Cell Division
Cells, Cultured
Female
Fibrin
Fluorescent Antibody Technique
Giant Cells
Humans
Phenotype
Placental Hormones
Plastics
Pregnancy
Trophoblasts

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