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Article

Chromatic and luminance contrast sensitivities in asymptomatic carriers from a large Brazilian pedigree of 11778 Leber hereditary optic neuropathy.

Investigative ophthalmology & visual science - 1 Dec 2005

Ventura Dora Fix, Quiros Peter, Carelli Valerio, Salomão Solange R, Gualtieri Mirella, Oliveira André G F, Costa Marcelo F, Berezovsky Adriana, Sadun Federico, de Negri Anna Maria, Sadun Alfredo A

Abstract excerpt

PURPOSE: To determine whether asymptomatic 11778 LHON carriers demonstrated impairments in (1) chromatic red/green (R/G) and blue/yellow (B/Y) contrast sensitivity functions (CSF) and in (2) luminance contrast sensitivity functions in the spatial CSF (SCSF) and temporal CSF (TCSF) domains. METHODS: Twenty-five carriers (8 male, 17 female; 34.1 +/- 15.1 years of age) of homoplasmic 11778 LHON from the same...

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PMID: 16303983
DOI: 10.1167/iovs.05-0455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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