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Article

Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat.

Frontiers in neuroendocrinology - 1 Jan 2000

Szyf Moshe, Weaver Ian C G, Champagne Francis A, Diorio Josie, Meaney Michael J

Abstract excerpt

Increased levels of pup licking/grooming and arched-back nursing by rat mothers over the first week of life alter the epigenome at a glucocorticoid receptor gene promoter in the hippocampus of the offspring. Differences in the DNA methylation pattern between the offspring of High and Low licking/grooming--arched-back mothers emerge over the first week of life, are reversed with cross-fostering, persist into...

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Share to Corticotropin-Releasing Hormone
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Glucocorticoid

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Source

Identifiers

PMID: 16303171
DOI: 10.1016/j.yfrne.2005.10.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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