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Article

chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis.

Developmental biology - 15 Dec 2005

Rojas-Muñoz Agustin, Dahm Ralf, Nüsslein-Volhard Christiane

Abstract excerpt

Despite the importance of the retinal pigment epithelium (RPE) for vision, the molecular processes involved in its specification are poorly understood. We identified two new mutant alleles for the zebrafish gene chokh (chk), which display a reduction or absence of the RPE. Unexpectedly, the neural retina (NR) in chk is specified and laminated, indicating that the regulatory network leading to NR development is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16300752
DOI: 10.1016/j.ydbio.2005.08.046

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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