Article
Differentiation of human adult CD34+ stem cells into cells with a neural phenotype: role of astrocytes.
Experimental neurology - 1 Feb 2006
Reali Camilla, Scintu Franca, Pillai Rita, Cabras Stefano, Argiolu Francesca, Ristaldi Maria Serafina, Sanna Maria Adele, Badiali Manuela, Sogos Valeria
Abstract excerpt
It has recently been reported that adult hematopoietic stem cells can differentiate into neural cells, opening new frontiers in therapy for neurodegenerative diseases. In this study, adult human hematopoietic stem cells (HSCs) were isolated via magnetic bead sorting, using a specific CD34 antibody and cultured with human astrocyte culture conditioned medium (ACM). In order to evaluate their differentiation into...
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