Article
Fetal human hematopoietic stem cells can differentiate sequentially into neural stem cells and then astrocytes in vitro.
Journal of hematotherapy & stem cell research - 1 Feb 2003
Hao Hsiao-Nan, Zhao Jane, Thomas Ronald L, Parker Graham C, Lyman William D
Abstract excerpt
In some rodent models, there is evidence that hematopoietic stem cells (HSC) can differentiate into neural cells. However, it is not known whether humans share this potential, and, if so, what conditions are sufficient for this transdifferentiation to occur. We addressed this question by assessing the ability of fetal human liver CD34(+)/CD133(+)/CD3(-) hematopoietic stem cells to generate neural cells and...
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