Article
Variants of the SFTPA1 and SFTPA2 genes and susceptibility to tuberculosis in Ethiopia.
Human genetics - 1 Feb 2006
Malik S, Greenwood C M T, Eguale T, Kifle A, Beyene J, Habte A, Tadesse A, Gebrexabher H, Britton S, Schurr E
Abstract excerpt
Lungs are the central organ affected and targeted by Mycobacterium tuberculosis and immune processes in the lung are of critical importance in the pathogenesis of tuberculosis. A major lung defense against invading pathogens is provided by surfactant protein A, a multi-chain protein encoded by the SFTPA1 and SFTPA2 genes. Here, we investigated polymorphisms in the SFTPA1 and SFTPA2 genes for association with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
